Imavita released the use of OCT (Optical Coherence Tomography) for in vivo imaging in the following applications:
- Atopic dermatitis / Oxazolone & IL23 models
- Psoriasis / IMQ & IL23 models
- Acne / Rhino mouse model (epidermis hyperplasia)
This imaging technique is available for in vivo (isofluran anesthesia) and/or ex vivo imaging and permits to accelerate evaluation of efficacy of compounds during course of projects or on sample collection.
Image example (atopic dermatitis model / ear):
Imavita developed a quantification algorithm to permit measurement of epidermis thickness immediatley after image capture. Correlation and validation of this imaging biomarker was fully performed in comparison to histology.
Release of in vivo OCT imaging in preclinical models was performed on November 2018.