Imavita released the use of OCT (Optical Coherence Tomography) for in vivo imaging in the following applications:

  • Dermatology
    • Atopic dermatitis / Oxazolone & IL23 models
    • Psoriasis / IMQ & IL23 models
    • Acne / Rhino mouse model (epidermis hyperplasia)

This imaging technique is available for in vivo (isofluran anesthesia) and/or ex vivo imaging and permits to accelerate evaluation of efficacy of compounds during course of projects or on sample collection.

Image example (atopic dermatitis model / ear):

Imavita OCT imaging

Imavita developed a quantification algorithm to permit measurement of epidermis thickness immediatley after image capture. Correlation and validation of this imaging biomarker was fully performed in comparison to histology.

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