Imavita / Preclinical imaging

Atherosclerosis models in rodents

  • Mouse atherosclerosis model or rat atherosclerosis model
  • Transgenic rodent models ApoE or LDLR KO + feeding
  • Atheroma plaques imaging / longitudinal studies (SPECT/CT, FMT)
  • Histology / macroscopic evaluation of lesions
  • Quantitative imaging biomarkers of atherosclerosis

Atherosclerosis models in non-rodents

  • Rabbit atherosclerosis model
  • Rabbit feeding (cholesterol chow / High Cholesterol Diet)
  • Surgical de-endothelization for induction of inflammatory atheroma
  • Destabilization of atheroma plaques (snake venom injection or de-endothelization)
  • Atheroma plaques imaging / longitudinal studies (SPECT/CT, FMT)
  • Histology / macroscopic evaluation of lesions
  • Quantitative imaging biomarkers of atherosclerosis

For additional informations on these models or on other preclinical models in the cardiovascular/atherosclerosis area, please inquire.