Osteo-articular pathologies

Bone healing / Osteoporosis model

Imavita preclinical model in osteo-articular pathologies

BMD evaluation by CT in femur of osteoporosis preclinical model

  • Osteoporosis model alone or bone healing in normal model (no osteoporosis) or in osteoporosis model
  • Healing in bone perforated induced model
  • Bone Mineral Density (BMD) evaluation (terminal) for osteoporosis evaluation
  • SPECT/CT imaging (99mTc medronate)
  • Classical approach using histology on terminal sampling
  • Longitudinal design / Repeated measurement with imaging
  • Micro-CT (ex vivo)
    • Bone Mineral Density (BMD)
    • Trabecular bone morphometrics

Rheumatoid Arthritis model

Imavita preclinical model osteo-arthritis

SPECT-CT (mouse knee)

  • CIA / Freund adj. Induction
  • SPECT/CT & FMT imaging of inflammation
  • Macroscopic eval. / scoring

Projects still on development at Imavita

For additional informations on these models or on other preclinical models in osteo-articular pathologies, please inquire.