Proteoglycan-induced Ankylosing Spondylitis model (AS)

The pathology of ankylosing spondylitis (AS) and related spondyloarthropathies (SpA) characteristically involve a sacroiliitis and inflammation of the intervertebral discs (IVD) in the lumbar spine, and an enthesitis at sites of ligamentous insertions into bone.

• Proteoglycan (PG) induced model / Freund adj. Induction
• FMT / PET imaging of inflammation
• CT imaging of bones / skeleton
• Macroscopic eval. / scoring

Model stills on development at Imavita.
For additional informations on this model or on other preclinical models in osteo-articular pathologies, please inquire.